Get a Bitcoin Address
Download the client to your PC from: bitcoin.org

Setup a bitcoin miner

ATI/AMD Users
You may need to update your video drivers or download and install the AMD Stream SDK from HERE before you can begin mining

Windows
Download GUIMiner: HERE


GUIMiner options
Server: Other
Host: arsbitcoin.com
Port: 8344
Username: <your user name>.<miner name> For example, BurningToad.default
Password: <your miner password (default miner password is 'default')>
You can view or edit your miner accounts in Account Details.
Device: Select the graphics card/cpu you would like to use
Extra Flags: Can be blank, but "-v -w128 -f 80" works well for ATI cards.

Linux
Check out Phoenix: forum post.